There's nothing more epic than two manly men fighting each other to the Internet death
for fame and glory. Yesterday, Fabio challenged the Old Spice Guy (Isaiah Mustafa) to a battle of viral superstardom.



Only one Old Spice Guy can exist, and Fabio is hoping that you’ll pick the New Old Spice Guy over the original. But, the Old Spice Guy isn’t standing down: He’s accepted the Mano A Mano en el Bano challenge.



This might be the biggest Web battle of the hearts and minds of the YouTube population, but there’s been other challenges and showdowns before. Here’s some of our favorites...

David versus The Drugs

Hang in there kid, we’ve all been there. It will be over soon enough.



Cat versus Washing Machine

Don’t let the machine fool you: It’s actually the cat that’s spinning the wheels



Puppies versus Cat

In a previous life, this Cat was a for-hire assassin. I wouldn’t mess with her either, puppies.



Obama Girl versus Giuliana Girl

The tension between the two girls is still less than the tension between the GOP and the
Democrats over the Debt talks.



Mens vs. Women’s brains

Finally the questions that has raged on for centuries: Why do the opposite sexes think differently? It’s all rooted in the brain, my dear Watson.